ROLE OF SH3GLB1 IN THE REGULATION OF CD133 EXPRESSION IN GBM CELLS

Role of SH3GLB1 in the regulation of CD133 expression in GBM cells

Abstract Background Glioblastoma (GBM), a malignant brain tumor, has poor survival outcomes due to hindigyanvishv.com recurrence or drug resistance.We found that SH3GLB1 is a crucial factor for cells to evade temozolomide (TMZ) cytotoxicity through autophagy-mediated oxidative phosphorylation, which is associated with CD133 levels.Therefore, we pro

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